Key takeaways
- Ubrelvy tablets are taken as needed to treat symptoms caused by migraine episodes.
- You’ll take Ubrelvy when you start to have migraine symptoms. If needed, you can take another dose 2 hours later.
- You should not take more than 200 milligrams (mg) of Ubrelvy in a 24-hour period. And you should not use it for more than eight migraine episodes in a month.
The active ingredient in Ubrelvy is ubrogepant. It belongs to a group of drugs called calcitonin gene-related peptide (CGRP) antagonists. It’s important to note that Ubrelvy is not prescribed to prevent migraine episodes.
This article describes the dosages of Ubrelvy, as well as its strengths and how to take it. To learn more about Ubrelvy, see this Ubrelvy overview.
The dosing table shown here highlights the usual dosages of Ubrelvy. All doses are listed in milligrams (mg).
Be sure to read on for more details.
| First dose (when symptoms begin) | Second dose, as needed (2 hours after first dose) | Maximum dosage in 24 hours |
|---|---|---|
| 50 mg or 100 mg | 50 mg or 100 mg | 200 mg |
Ubrelvy form
Ubrelvy comes as tablets that you swallow.
Ubrelvy strengths
Ubrelvy is available in two strengths:
- 50 mg
- 100 mg
The typical starting dose of Ubrelvy is 50 mg or 100 mg, which you take when you have a migraine episode. If the first dose doesn’t treat your migraine symptoms, you can take a second dose after 2 hours. The maximum dose for migraine episodes is 200 mg in 24 hours.
It’s not known whether it’s safe to take Ubrelvy for more than eight migraine episodes in 30 days. Be sure to keep track of all your migraine episodes in a month and how much Ubrelvy you take.
If you’re concerned about the frequency of your migraine episodes, talk with your doctor. If you’re experiencing more than eight migraine episodes per month, they may suggest other treatment options. This includes medications to help prevent migraine episodes.
These are the dosages commonly used or recommended. But be sure to take the dosage your doctor prescribes for you. They’ll determine the best dosage to fit your needs.
Dosage adjustments
Your doctor may need to adjust your Ubrelvy dosage if you have serious liver disease or kidney disease. With these conditions, Ubrelvy can stay in your body longer and increase your risk of side effects from this drug.
If you have stage 4 kidney disease, your doctor will recommend that you take only 50 mg of Ubrelvy for the first dose and, if needed, another 50 mg for the second dose. If you have end stage kidney disease, your doctor will recommend a different medication for you.
If you have Child-Pugh class C liver disease, your doctor will also recommend that you take only 50 mg for both the first and second doses.
If you have problems with your liver or kidneys, talk with your doctor before taking Ubrelvy. They may want to order blood tests to check the health of your liver and kidneys before prescribing this drug for you.
Here are answers to some commonly asked questions about Ubrelvy’s dosage.
What is the maximum Ubrelvy dose per month?
Taking Ubrelvy to treat more than eight migraine episodes per month is not recommended. Studies haven’t been done to test the safety of taking Ubrelvy more than this. If you’re experiencing more than eight migraine episodes per month, you can talk with your doctor to discuss other treatment options.
Is there a maximum Ubrelvy dose per day?
Yes. The maximum daily dose of Ubrelvy is 200 mg. Taking more than 200 mg in a 24-hour period increases your risk of side effects.
If you have serious kidney disease or liver disease, your doctor may lower the maximum dose of Ubrelvy you can take in 24 hours.
If the maximum dose of Ubrelvy doesn’t treat your migraine symptoms, ask your doctor about other treatment options.
The dosage of Ubrelvy that your doctor prescribes may depend on several factors. These include:
- the severity of your migraine symptoms
- other medications you may be taking
- other conditions you may have (see “Dosage adjustments” in the “What is Ubrelvy’s dosage?” section earlier in this article)
Ubrelvy comes as tablets that you swallow. You can take the medication with or without food.
It’s important to note that you should not take a second dose of Ubrelvy if you’ve consumed grapefruit or grapefruit juice within 24 hours of your first dose. Taking Ubrelvy with grapefruit can increase your risk of side effects from Ubrelvy because grapefruit slows the removal of the drug from your body.
Is Ubrelvy used long term?
Yes, Ubrelvy is usually prescribed as a long-term treatment. If you and your doctor determine that it’s safe and effectively relieves your migraine symptoms, you’ll likely take it as needed for the long term.
Do not take more Ubrelvy than your doctor prescribes, as this can lead to serious side effects. If you have liver or kidney problems, your risk of side effects is greater because the drug can stay in your body longer.
If Ubrelvy isn’t working to treat your migraine symptoms, do not take more than the maximum allowable dosage. Instead, talk with your doctor about other options to manage migraine symptoms.
What to do in case you take too much Ubrelvy
Call your doctor right away if you think you’ve taken too much Ubrelvy. You can also call 800-222-1222 to reach America’s Poison Centers or use its online resource. But if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
