Ubrelvy (ubrogepant) is a prescription oral tablet used for fast-acting relief of migraine symptoms in adults. Ubrelvy may not be safe to take while pregnant or breastfeeding.
If you can become pregnant, it’s important to consider whether Ubrelvy is a safe option for you.
It’s not known whether you can take Ubrelvy when you’re pregnant. In animal studies, Ubrelvy caused harmful effects in offspring born to pregnant animals given the drug. Based on these animal studies, the drug may cause fetal harm. But it’s important to note that what happens in animal studies may not occur in humans.
If you take Ubrelvy while pregnant, consider enrolling in the EMPRESS Pregnancy Registry. This pregnancy registry collects information about Ubrelvy’s safety during pregnancy. To learn more or to sign up, visit the registry website or call 833-277-0206.
Migraine and pregnancy
According to published data, people with migraine may have a higher risk of preeclampsia and high blood pressure during pregnancy.
Because of this, you and your doctor should discuss the risks and benefits of taking Ubrelvy while pregnant versus not treating your condition during pregnancy. If they determine Ubrelvy is not right for you, your doctor may recommend another treatment option, such as sumatriptan, Nurtec ODT, Qulipta, or Ajovy.
It’s not known whether Ubrelvy is safe to take while breastfeeding.
Data from a lactation study of 12 healthy adult females showed that ubrogepant (the active ingredient in Ubrelvy) is excreted in breast milk in low amounts. But no data exist to indicate the possible effects of ubrogepant on breastfed infants.
If you’re currently breastfeeding or planning to breastfeed, talk with your doctor before starting Ubrelvy treatment.
Note: The use of binary terms such as “male” and “female” in this article reflects the language of the sources we’ve used. Unless otherwise noted, it’s unclear whether the research we reference included participants with expansive gender identities.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.